The Ozone Enigma in Medicine The Biochemical Relationship between Ozone and Body Fluids May Account for its Biological, Therapeutic and Toxic Effects
V. BOCCI, L. BIANCHI,A. LARINI
Department of Physiology, University of Siena; Italy
Revista o sitio electrónico (URL) donde se publicó
Rivista Italiana di Ossigeno-Ozonoterapia 2: 113-120, 2003
Ozone, antioxidants, oxidative stress, low-back pain
The aim of this review was twofold. The first was to correlate the empirically determined ozone dose to the presence and amount of antioxidant capacities present in several body fluids and tissues.Although some data are uncertain, we have reached the conclusion that ozone must be administered with great care and that the doses, so far assessed by trial and error, are reasonable and apparently useful.What is most surprising is that a theoretically offensive stimulus, represented by a sudden administration of oxygen-ozone, is able to reactivate natural defence mechanisms in a pleiotropic fashion restoring health and eliminating pain.
The second aim was to describe how ozone is administered in orthopaedic diseases and to discuss hypothetical mechanisms of action.While we feel that the strategy of the most ozone is not advisable, we are unable to explain the “ozone paradox”.This is a great challenge for both proponents and opponents of ozone therapy and the problem must be solved because the wide use of ozone could benefit millions of suffering people who currently do not receive sufficient medical attention.