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The intensive care of lower limb diabetic wounds: our 5 years experience in 121 patients treated topically with ozone as an ADJU

Título
The intensive care of lower limb diabetic wounds: our 5 years experience in 121 patients treated topically with ozone  as an ADJU
Autores

Noam Calderon, Teddy Kaufman, Leonid Bryzgalin, Munir Awad

Division of Plastic and Reconstructive Surgery, Bnai-Zion Medical
Center, Haifa

Abstract

The purpose of this study was to critically assess the efficacy of topical OZONE treatment of chronic diabetic and PVD ulcers of
the lower limb as an adjunctive modality to serial debridements of the wounds; topical and systemic antimicrobial agents and,
frequent dressing changes.

Patients: 121 patients were treated between 6/1997 to 8/2001. 3 were excluded from the study. 66/118 (56%) were diabetic, while 38/66 (57.6%) suffered also of peripheral vascular disease. 15/66 (22.7%) were discontinued due to physiological disturbances. 52/118 suffered of venous ulcers, and 8/52 were discontinued.

Modality of treatment: consisted of -repeated wound cultures (X 3/week), topical and systemic antimicrobial agents according to wound colonization, serial wound and osteomyelytic bone debridements, dressing changes X 3/day in the presence of our Resident and, topical Ozone X 3/week.

Results:21 patients who were previously subjected to b/k amputation in another hospital – healed completely. The mean wound duration prior to treatment was – 14.1 months. The mean healing time was – 49 days. The mean number of Ozone treatments was 25.7/patient. 23/118 (19.5%) – patients were discontinued from the trial. 79/95 (83.16%) – were fully healed, 29/79 (36.7%) – were skin grafted, 16/95 (16.8%) – were diagnosed as non-response patients, 4 of them underwent b/k limb amputation.

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